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A model of Cerebrospinal Fluid (CSF) flow in the human craniovertertebral junction
The goal of this project is to create a life-size physical model of the human hindbrain and upper cervical spinal canal. This will be used to study how varying dimensions affect CSF flow in terms of pressure. Oscillatory flow is required in the model, and pressure must be quantifiable.
The prototype:

Shown above is our final design. The model is made out of a clear polycarbonate sheet cut into blocks. A hole is drilled at the center of each block so that a funnel shape is formed inside when the blocks are held together. The three tubes attached to the top of the blocks are used to roughly measure pressure. In the future, a transducer may be inserted in place of these tubes for a more accurate measurement. The blocks are held together by two steel rods. The model is attached at both ends to tubes connected to the pump.

Our schematic diagram is shown above. You can see the outline of the funnel shape inside the model here.
The pump:

Shown above is a picture of the pump we will use, and a close-up of the piston which pushes the green liquid through the tubes and into the module. This pump can generate oscillatory flow.

This is a module attached to the pump. Our module will be connected in the same way.
| Week | Reporting Period Beginning | Activities |
|---|---|---|
| 1 | January 23 | Selected project. Formed teams and assigned team roles. Met with client. |
| 2 | January 30 | Did some research to gain further understanding of project. |
| 3 | February 6 | Developed PDS. |
| 4 | February 13 | Brainstormed potential designs. Met with client to gain further insight into the design and to show him some of our ideas. |
| 5 | February 20 | Evaluated three possible designs. Began writing mid-semester report. |
| 6 | February 27 | Assembled and rehearsed powerpoint presentation. |
| 7 | March 5 | ORAL PRESENTATIONS. PowerPoint slides on website by 10:00 am; keep website up to date. |
| 8 | March 12 | The mid-semester paper, PDS, and design notebooks were handed in. |
| 9 | March 19 | Spring break. |
| 10 | March 26 | Met client to ask questions and see the pump. |
| 11 | April 2 | Looked for materials at hardware stores, catalogs, and online. Adjusted design. |
| 12 | April 9 | Meet with client. Cut polycarbonate. Begin assembling model. |
| 13 | April 16 | Assemble the model. |
| 14 | April 23 | Prepare for final presentation. |
| 15 | April 30 | FINAL POSTER PRESENTATIONS. Hand in written report and notebook. Final meeting with advisor. |
| Mid-semester Powerpoint Presentation (Mar 4 2004, 373 kb) | |
| PDS Report (Mar 7 2004, 35 kb) | |
| Preliminary Design Report (Mar 13 2004, 300 kb) | |
| Final Poster Presentation (Apr 30 2004, 4261 kb) | |
| Final Report (May 4 2004, 3687 kb) |