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To form PEG macromer-based hydrogels on a latex Foley catheter surface in an interfacial photopolymerization process and to screen the coatings for interactions with cells and media that mimic physiologic fluids. It is hypothesized that these coatings will resist fouling and may be useful for reducing infections resulting from the use of urinary catheters.
From left to right: Patrick Schenk, Darshan Patel, Brett Mulawka, and Ben Roedl
Running experiments to find the ideal ethyl eosin stain concentration that will produce desired adhesion, thickness, and protein adsorption.
| Week | Reporting Period Beginning | Activities |
|---|---|---|
| 1 | January 26 | Contacted client, discussed outreach options, researched latex. |
| 2 | February 2 | Received ethyl eosin, researched surface properties and modification of latex. |
| 3 | February 9 | Arranged for Foley catheters, acquired relevant journal articles. |
| 4 | February 16 | Contacted catheter companies, further latex research, reviewed biomaterial journals. |
| 5 | February 23 | Discussed different possible reactions involving latex, began work on mid. semester presentation. |
| 6 | March 2 | Tested latex-PEG adhesion with eosin in bulk solution, vulcanization research, work on mid. semester presentation. |
| 7 | March 9 | Researched vulcanization and PEG-latex interactions, Lab work to create more solutions. |
| 8 | March 16 | Work on Science Expeditions experiments and presentation (Outreach), Created more eosin solution. |
| 9 | March 23 | Presented outreach project at Science Expeditions, researched protein adhesion testing techniques |
| 10 | March 30 | Contacted client and work towards final design. |
| 11 | April 6 | Began work on final report, restarted adhesion and thickness testing on substrates. |
| 12 | April 13 | Split into groups working on coating optimization and protein adhesion, protein assay research, started protein adhesion experiment. |
| 13 | April 20 | Work on final report and presentation, continued lab experiments. |
| 14 | April 27 | Work on final poster presentation, analyzing experimental results. |
| 15 | May 4 | Poster presentation, work on technical report |
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Mid. Semester Presentation (Mar 12 2007, 1413 kb) |
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PDS - Product Design Specification (Mar 14 2007, 23 kb) |
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Final Poster (May 4 2007, 418 kb) |
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Technical Report (May 9 2007, 146 kb) |
