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Interpenetrating networks (IPNs) are a type of biomaterials that polymerize in situ and have been used in drug delivery, wound healing, and tissue engineering applications. This design project involves the development of novel delivery mechanisms that should be clinically easy to use with improved storage life. Our device should safely, efficiently, and accurately aid in the administration of IPNs to a specific region.
Project and paper have been completed.
Team (from left): Max Michalski, Ashley Huth, Adam Rieves, Claire Flanagan
Gelatin which dissolved in HCl and gelled after being centrifuged.
Gelatin which did not dissolve into solution with HCl added.
| Week | Reporting Period Beginning | Activities |
|---|---|---|
| 1 | September 8 | Assigned team roles, began research, and contacted client |
| 2 | September 15 | Met with client, drafted PDS, and redefined problem statement |
| 3 | September 22 | Set up meeting with Tracy, reviewed notes sent by Tracy, updated PDS |
| 4 | September 29 | Met with Tracy, synthesized PEGda, created IPN |
| 5 | October 6 | Met and discussed problem approach, Contacted Prof. Kao, Established new research approach, Researched Gelatin |
| 6 | October 13 | Obtained gelatin and began research varying pH, Created mid-semester presentation |
| 7 | October 20 | Powerpoint presentation. |
| 8 | October 27 | Met with Prof. Kao and discussed research and future approach. Gathered supplies from Kao Lab and ordered different gelatin blooms. |
| 9 | November 3 | Researched surfactant and varied gelatin blooms at room temperature. |
| 10 | November 10 | Took pictures of results from bloom variation experiment with extreme pH’s and physiological buffers. Discussed Results with Prof. Kao. |
| 11 | November 17 | Tested citrate buffer as the solvent for performing a full test of IPN creation. |
| 12 | December 1 | Created IPN with research techniques used so far. |
| 13 | December 8 | Tested repeatability with designed IPN tecnhique and created poster. |
| 14 | December 15 | Finished design notebooks and final paper. |
| 15 | December 22 | Cleaned materials from Prof. Master’s Lab |
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Mid-Semester Presentation (Oct 19 2006, 273 kb) |
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Mid-Semester Report (Oct 25 2006, 374 kb) |
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PDS (Dec 3 2006, 81 kb) |
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Final Poster (Dec 7 2006, 1867 kb) |
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Final Paper (Dec 13 2006, 688 kb) |
