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Biomedical Engineering Design Projects

Microencapsulation of tissues and cells for treatment of hormone-related diseases

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Project Overview

To design polyethylene glycol diacrylate (PEGdA) hydrogels for the encapsulation of Murine Leydig Tumor Cells (MLTC-1) in an effort to increase cell viability and testosterone secretion. The PEG-dA hydrogels must provide immunoprotection and allow for the effective diffusion of oxygen, nutrients, hormones, and metabolic wastes. The overall goal is to restore the testosterone level of castrated mice via injection or implantation of the PEG-dA encapsulated cells.

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Project Status

Team Picture

Preparation for Poster Presentation

Progress Report Archive.

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Project Timeline

Week Reporting Period Beginning Activities
1 September 8 Form teams, select project, contact client, email team roles to advisor
2 September 15 Literature sesarch, meet with client
3 September 22 Develop understanding of project, develop PDS
4 September 29 Brainstorm
5 October 6 Decide on design alternatives
6 October 13 Work on presentations
7 October 20 Work on presentations
8 October 27 Put PowerPoint presentation on team web site by 10:00am
9 November 3 Hand in written report including PDS, submit design notebooks for advisor review
10 November 10 Decide on final design
11 November 17 Work on design
12 December 1 Work on design
13 December 8 Work on design
14 December 15 Hand in written report and notebook to advisor
15 December 22 Final meeting with advisors

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Presentations and Reports

pdf icon Project Design Specification (Oct 26 2006, 26 kb)
ppt icon Mid-semester Presentation (Oct 27 2006, 375 kb)
ppt icon Final-Poster Presentation (Dec 8 2006, 448 kb)

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Contact Information

Project Team

Project Advisor and Client

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Owner: Willis Tompkins, Ph.D.
Author: Eric Lee
Webmaster: Andrew L. Wentland
Created: Oct 12 2006
Content updated: Dec 10 2006

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