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Biomedical Engineering Design Projects

MRI-Compatiable Bioreactor for Viewing Cartilage Loading

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Due to proprietary concerns, this project is password protected. The following project description will give you a brief overview of the project. If you would like more information, please contact a member of the project team--they will be able to share whatever information they can with you.

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Project Overview

The objective of this project is to develop a bioreactor to secure cartilage tissue during magnetic resonance (MR) scanning and provide mechanical loading during this scanning. Cartilage tissue cultures are currently grown in vitro for subsequent implantation into the body between joints where the cartilage has been damaged by osteoarthritis or injury. Our bioreactor will be used to protect these small tissue cultures and apply a compressive force to determine if the tissue is fully developed. This will provide a non-destructive method to test the tissue cultures unlike current approaches.

Our team from left to right: Luisa Meyer, Sarah Springborn, BK Huh, and Sarah Czaplewski

Scanner used to image tissue cultures

Above is the 4.7T animal scanner used to image cartilage tissue cultures.

Coil of 4.7T animal scanner

This is the coil of the 4.7T scanner. It is 3 inches in diameter and 6 inches long. Our bioreactor must fit inside of it.

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Contact Information

Project Team

Project Advisor and Client

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Owner: Willis Tompkins, Ph.D.
Author: Sarah Czaplewski
Webmaster: Andrew L. Wentland
Created: Sep 27 2009
Content updated: Nov 21 2009

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