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The goal of this project is to develop an endotracheal tube adaptor that will be used to consistently deliver aerosolized medications to anesthetized patients during surgery. Recent changes to the aerosolized medicine canisters due to environmental concerns over the propellant have rendered current adaptors ineffective. Our client would prefer an adaptor that either works with the patients Multi Dosed Inhaler (MDI) or with the new medication canister (Albuterol or Ipratropium).
Team Members from left to right:
Ryan Childs, BSAC
Evan Joyce, Leader
Tim Barry, BWIG
Ozair Chaudhry, Communicator
Pictures of our team at the 3rd Annual Tong Competition
Professors Tompkins and Thompson serenading the crowd
Final Design:
We created a 3D solidworks design of our prototype, which was then fabricated by the UW-Madison Physics Machine Shop. Our final prototype is made of stainless steel and successfully addresses all of our clients needs. Our prototype efficiently aerosolizes albuterol, and is universally compatible with all types of HFA albuterol canisters. Additionally, the prototype nozzle is designed to have an airtight friction fit with a standard-size Luer port found on a commonly used anesthesia elbow. This increases the compatibility of our prototype and allows it to be used in nearly any anesthesiology lab. The prototype is ergonomically friendly and only requires one hand to use. It is also lightweight and requires minimal force to actuate. Along with all these advantages, the relative simplicity of the geometry allows for injection molding, which in turn would allow for mass production and commercialization of our prototype.
Testing:
We have completed particle size and distribution testing of our prototype using a Malvern laser diffractor. These tests indicate that our prototype is comparable to the old adaptor used by the UW-Hospital (bronchodilator tee) at aerosolizing albuterol. We plan to perform several tests with an MOUDI (Multi-Orifice Uniform Deposit Impactor) Cascade Impactor to quantitatively analyze the size of the aerosolized particles generated by our prototype. We will also analyze the particle size generated by the bronchodilator tee and a patient’s handheld MDI to compare to the results of our prototype.
Figure 1. Data from Malvern Laser Diffraction testing
Figure 2. MOUDI Cascade Impactor
Future Work:
We plan to apply for a provisional patent for our prototype in the near future, as suggested to our group by a doctor at the UW-Hospital and colleague of our client. We will also make any necessary adjustments to our product to increase its efficiency. We also plan on contacting Boehringer Labs, the medical equipment and supply company responsible for manufacturing and distributing the bronchodilator tee to discuss the possibility of commercializing our prototype.
| Week | Reporting Period Beginning | Activities |
|---|---|---|
| 1 | January 23 | |
| 2 | January 30 | Assigned team roles, developed preliminary schedule, met with client and discussed project specifications |
| 3 | February 6 | Found information on relevant patents and the anesthesia ventilation circuit, began brainstorming, had second meeting with client to obtain important instruments, attended Solidworks seminar as a team |
| 4 | February 13 | Researched possible materials, found pertinent information regarding cleaning method of UW Hospital (MetriCide solution), began brainstorming design alternatives, finalized PDS |
| 5 | February 20 | Began developing design matrix criteria and alternatives, chose top three design choices, continued researching possible materials, began work on midsemester powerpoint presentation |
| 6 | February 27 | Finished design matrix, evaluated each of the three design alternatives against matrix, finished rough draft of powerpoint presentation, met with client to discuss design alternatives, researched possible methods of fabrication for prototype |
| 7 | March 6 | Midsemester Presentation in 1152 ME, divded up work for midesemester report, began contacting companies regarding fabrication and testing |
| 8 | March 13 | Began researching Luer locks, began narrowing down list of companies for fabrication |
| 9 | March 20 | Developed preliminary SolidWorks model, researched testing options (SolidWorks software, questionnaire, etc.), found two shops on campus capable of manufacturing prototype, contacted GlaxoSmithKline regarding funding for project |
| 10 | March 27 | Completed SolidWorks model and made compatible with Luer port on standard anesthesia elbow, researched more testing ideas such as laser diffraction and cascade impactor testing |
| 11 | April 3 | Received quote and submitted design to physics lab for fabrication, developed a survey for UW-hospital workers to evaluate our new design |
| 12 | April 10 | Fabrication of prototype complete with perfect friction fit with Luer port, contacted 3M regarding Bernoulli’s equations for further evaluation of our prototype, found a lab on campus with a cascade impactor for testing particle sizes generated by prototype, began working on poster for tong competition |
| 13 | April 17 | Made minor adjustment to nipple dimension of prototype to increase efficiency, received constructive feedback from client and colleagues through survey, developed testing protocol for laser diffractor and cascade impactor tests, set up a meeting with professor regarding cascade impactor testing, received feedback from GSK regarding prototype, continued work on prototype |
| 14 | April 24 | Finished laser diffraction testing, met with fluid dynamics professor Timothy Shedd and received excellent feedback on the efficiency of our prototype, met with Mike Olson regarding cascade impactor testing and opted to delay tests until summer, completed poster for tong competition |
| 15 | May 1 | Contacted WARF regarding Invention Disclosure Report and patent information, finished writing Semester Report |
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Final PDS (Apr 30 2009, 80 kb) |
|
Midsemester Powerpoint Presentation (Apr 30 2009, 1798 kb) |
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Midsemester Report (Apr 30 2009, 5816 kb) |
