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To reduce the risk of brain injury and slow cerebral reperfusion in post-cardiac arrest patients, hypothermia is induced during helicopter or ambulance transport. Hypothermia is induced by infusing saline at 4°C to reach a core body temperature of 32°C to 34°C. To ensure that saline enters the body at 4°C, a method of cooling and maintaining the saline temperature is needed. The method must consider the space constraints of an ambulance or helicopter. Alternative methods, including evaporative cooling, can be used in conjunction with cold saline to induce hypothermia more rapidly. Upon arrival at the hospital, methods are already in place to maintain hypothermia. For effective implementation in Emergency Medical Services nationwide, the method must be cost-effective.