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Trans-arterial chemoembolization simulator

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Project Overview

This project involves the development of a functional MRI liver phantom. The phantom will include the major vasculature of the liver and will be active (fluid will be pumped through it.) The purpose of the phantom is to train surgeons who will preform the TACE procedure.

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Project Status

Currently we have developed more than one model of the hepatic vasculature. We are now moving to purchasing parts and building a physical prototype. This model will be built out of Tygon tubing.


Team Members
TeamPic
(From left to right): Ben Engel, Ryan Carroll, Justin Schmidt, Eric Printz


Modeling

A preliminary model (below) constructed out of pipecleaners provides a good starting point for an advanced model.
A preliminary model of the hepatic circulation. Further detail of the pipe model.

A more advanced model is developed using Autodesk Maya 8.0

The model was developed by superimposing screenshots of a commercial 3D model and reproducing
the vasculature using extruded polygons with modified verticies. The four images below show
the process of creating the 3D model
Wireframe front view working copy. Solid/Wireframe perspective view. No segments are modeled.

Further work is conducted...
More work... More work...

Below details a near-finished model
A near finished rendering. A near finished rendering. A near finished rendering. A near finished rendering. A near finished rendering. A near finished rendering.

In the above figures the eight Couinaud segments are detailed as they come off of the main hepatic artery.
Using this model, we hope to create a physical model using tygon tubing.
Tygon tubing is commonly used in lab applications.


The final prototype has been developed and tested. Below are pictures of the finished prototype. For test results, see the poster presentation movie file below.
A near finished rendering. A near finished rendering. A near finished rendering.

Movies
Please follow these external links to access our movies
https://mywebspace.wisc.edu/rccarroll/Senior%20Year/Design/LiverRotat.zip
https://mywebspace.wisc.edu/rccarroll/Senior%20Year/Design/PosterPresentationRevised.mov.zip



Resources
Tygon Picture: http://www.highspeedpc.com/Merchant2/graphics/00000001/Tygon320.jpg
3D Modeling Using: Autodesk Maya 8.0

Progress Report Archive.

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Project Timeline

Week Reporting Period Beginning Activities
1 September 5 Obtained project, distributed team roles, contacted client and advisor, and set up meeting times.
2 September 12 Held team meeting to discuss project goals and direction. Individual grant review. Research. Established schedule/agenda for the semester. Tried to obtain a liver model containing vasculature.
3 September 19 Accomplished a team meeting and brainstorm session for our initial thoughts on how to create the vasculature. Obtained make and model number of flow pump for further investigation. Contacted Alan Wolf at doit for more information on the capabilities of the 3D printer. Developed working copy of PDS and performed a preliminary review of the document (more to be added throughout the semester)
4 September 26 Accomplished a team meeting to discuss initial need for parts. Gained approval to purchase Tygon tubing. Ordered tubing. Initiated contact with Dr. Rice - Liver Transplant Department at the University of Flordia. Started building 3D model in Maya.
5 October 3 Researched best practices for creating 3D vasculature using molding techniques. Contacted Shelley Medical to ask about vasculature modeling. Extensive 3D modeling in Maya. Received information from Dr. Rice.
6 October 10 Decided on creating vascular junctions by precisely cutting proper sized holes in the tubing and sufficiently securing it in place using silicon based epoxy. Finalization of 3D model using Maya. Developed midsemester presentation. Filmed midsemester presentation.
7 October 17 Begin looking into parts for vascular network modeling. Began experimenting with vascular junctions using Tygon tubing and silicone epoxy. Gave midsemester presentation.
8 October 24 Put together relay switch and power supply and control cabling. Determined and purchased material for enclosure. Experimented with creation of vasculature. Created mock enclosure.
9 October 31 Successfully created multiple vascular junctions. Discussed approach to controlling flow pump through use of analog signal. Contacted support at company called Labjack. Discussed vascular details with liver surgeon.
10 November 7 Significant progress in vascular creation. Developed parts list to complete phantom and sent in purchase. Began developing technique for enclosure creation.
11 November 14 Finalized vasculature and determined exact spatial relations within the phantom. Cut sides for enclosure, determined location of inlets and outlets, drilled all holes for inlets and outlets, and adhered sides together to create enclosure. Bought remaining necessary connectors and tubing to finalize phantom and interface device with existing tubing running to and from MR control room.
12 November 21 Transported phantom to UW hospital for testing.Phantom contractions was finalized and integrated with current pump and water lines. Integrity testing carried out to verify that the vasculature was leak proof, the box was leak proof, and that adequate flow was achieved in all of the vessels.
13 November 28 Imaging studies carried out to verify that phantom does not create significant artifact and that all physical characteristics of the phantom comply with the scanner and scan room. Created media for effective presentation (poster, videos).
14 December 5 Poster Presentation.
15 December 12 Finalization of all deliverables: website, notebooks, and paper.

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Presentations and Reports

ppt icon Midsemester Presentation (Oct 16 2008, 2344 kb)
avi icon Liver Vasculature 3D Model (Oct 16 2008, 655 kb)
pdf icon PDS - Product Design Specification ver. 2 (Oct 21 2008, 42 kb)
pdf icon Final Poster (Dec 11 2008, 1421 kb)
pdf icon Final Paper (Dec 12 2008, 1077 kb)

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Contact Information

Project Team

Project Advisor and Client

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Created: Sep 21 2008
Content updated: Jan 23 2009

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