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Significant dry eye is an affliction that affects up to ten million people in the United States. There are currently options available to treat the symptoms of dry eye, but a way to treat the causes and repair the damage has yet to be found. We aspire to design and fabricate a dissolving biogel that is capable of sustained release of epidermal growth factors that will work to maintain healthy epithelium and restore damaged tissue on the ocular surface.
| Week | Reporting Period Beginning | Activities |
|---|---|---|
| 1 | January 22 | Established team roles, met with client, conducted preliminary research, began writing PDS. |
| 2 | January 29 | Completed preliminary PDS, continued conducting background research, clarified information with client. |
| 3 | February 5 | Continued individual background research and discussed physical specifications of biogel technologies and their potential applications |
| 4 | February 12 | Met with client to help clarify design specifications, began research on alternate growth factors to EGF. |
| 5 | February 19 | Continued research on biogels and growth factors, determined design alternatives, began delegating sections of mid-semester report. |
| 6 | February 26 | Developed design matrix and began preparing for Mid-Semester Presentation. |
| 7 | March 5 | Group met to finalize and edit mid-semester report and updated PDS |
| 8 | March 12 | Gave our mid-semester presentation and set up a meeting with Dr. Murphy. |
| 9 | March 19 | Met with Dr. Murphy and obtained information on ordering starting materials for synthesizing biogel. |
| 10 | March 26 | Spring Break |
| 11 | April 2 | Met with Mike Toepke to dicuss methods for creating biogel. |
| 12 | April 9 | Group met to determine calculations for creating biogels, and initiated swelling testing. |
| 13 | April 16 | Started degradation testing and live/dead assay. |
| 14 | April 23 | Created poster for final presentation, analyzed dregradation testing and began writing final paper. |
| 15 | April 30 | Poster Presentation from 12pm - 2pm 5/7/2010 in ECB |
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Project Design Specifications (PDS) (May 11 2010, 98 kb) |
|
Mid-Semester Report (May 11 2010, 404 kb) |
|
Mid-Semester Presentation (May 11 2010, 1818 kb) |
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Poster (May 11 2010, 1934 kb) |
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Final Report (May 11 2010, 1917 kb) |
