(Access key: S).
Significant dry eye is an affliction that affects up to ten million people in the United States. There are currently options available to treat the symptoms of dry eye, but a way to treat the causes and repair the damage has yet to be found. We aspire to design and fabricate a dissolving biogel that is capable of sustained release of epidermal growth factors that will work to maintain healthy epithelium and restore damaged tissue on the ocular surface.
|Week||Reporting Period Beginning||Activities|
|1||January 22||Established team roles, met with client, conducted preliminary research, began writing PDS.|
|2||January 29||Completed preliminary PDS, continued conducting background research, clarified information with client.|
|3||February 5||Continued individual background research and discussed physical specifications of biogel technologies and their potential applications|
|4||February 12||Met with client to help clarify design specifications, began research on alternate growth factors to EGF.|
|5||February 19||Continued research on biogels and growth factors, determined design alternatives, began delegating sections of mid-semester report.|
|6||February 26||Developed design matrix and began preparing for Mid-Semester Presentation.|
|7||March 5||Group met to finalize and edit mid-semester report and updated PDS|
|8||March 12||Gave our mid-semester presentation and set up a meeting with Dr. Murphy.|
|9||March 19||Met with Dr. Murphy and obtained information on ordering starting materials for synthesizing biogel.|
|10||March 26||Spring Break|
|11||April 2||Met with Mike Toepke to dicuss methods for creating biogel.|
|12||April 9||Group met to determine calculations for creating biogels, and initiated swelling testing.|
|13||April 16||Started degradation testing and live/dead assay.|
|14||April 23||Created poster for final presentation, analyzed dregradation testing and began writing final paper.|
|15||April 30||Poster Presentation from 12pm - 2pm 5/7/2010 in ECB|
|Project Design Specifications (PDS) (May 11 2010, 98 kb)|
|Mid-Semester Report (May 11 2010, 404 kb)|
|Mid-Semester Presentation (May 11 2010, 1818 kb)|
|Poster (May 11 2010, 1934 kb)|
|Final Report (May 11 2010, 1917 kb)|
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