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Biomedical Engineering Design Projects

Molecular Antibody Protein Structure Model

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Project Overview

HIV is a virus that progressively leads to the development of acquired immunodeficiency syndrome (AIDS), a deadly condition in which the immune system collapses and fails to protect against infection. Our client, Marge Sutinen of the UW School of Medicine and Public Health, works to educate students on the permanent effects of HIV in her Contemporary Issues in HIV/AIDS Prevention course. She has asked our team to develop a 3D model that captivates the attention of a class of undergraduates and visually illustrates the HIV attachment to CD4 cells and the permanent effect it has on the body. This model will be used as an aid in demonstrating the irreversibility of contracting the HIV virus to persuade students to use preventative measures to protect themselves.

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Project Status

We have decided on a final design and we will begin the fabrication stage as soon as we order our materials.



Team Photo

OUR TEAM: Jon, Andy, Kim, & Kara

Progress Report Archive.

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Project Timeline

Week Reporting Period Beginning Activities
1 September 4 Picked our project and met the other members in our team; individually researched our topic and came up with questions for our client
2 September 11 Met with our client and received basic but vague expectations; researched more in depth about the process of HIV attachment to CD4 receptors; began brainstorming ideas of how to portray this process in a 3D model
3 September 18 Brainstormed more creative design ideas; wrote our preliminary PDS report; verified our research on the HIV process with Professor Li; discussed potential materials that could be used for the model
4 September 25 Came up with the three stages that we want to highlight with our model, and for each stage we decided on three different design proposals which we are going to present to our client so she can decide what design we will proceed with. We also researched possible materials that we can use to create our model.
5 October 2 Presented our designs ideas to our client and decided on the final design that we are going to pursue. Also redefined some of our specifications.
6 October 9 We decided on materials that we are going to use for our final design. We divided tasks and started working on our mid-semester paper and presentation.
7 October 16 We finalized and wrapped up all of our ideas and gave our mid-semester presentation to the class and worked on our mid-semester report.
8 October 23 We met with our advisor and recieved feedback from our mid-semester presentations. We are working to coming up with new design ideas that will enhance our final product.
9 October 30 We received feedback from our midsemester presentation and took the advisor’s thoughts about our project into consideration as we made many improvements to our design this week. We met with our advisor to get our new design approved. We will meet with our client this weekend to see if she likes our changes before we proceed with fabrication.
10 November 6 We met with our client this week and she approved our new design idea. We began purchasing materials and getting help from professors and advisors for the fabrication of our circuit.
11 November 13 We purchased all of the materials that we need for our project. We met with Amit in the BME lab to get started on the design for our circuit.
12 November 20 We began the fabrication of our cells and viruses. We molded them with clay first, but then ran into some problems and had to purchase plaster and a finish to make it secure. Then we painted all of the cells and viruses. We also started the fabrication of our circuit and display board.
13 November 27
14 December 4
15 December 11

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Presentations and Reports

pptx icon Mid-Semester Presentation (Oct 15 2009, 2392 kb)
pdf icon PDF - Mid-Semester Presentation (Oct 16 2009, 1161 kb)
pdf icon Product Design Specification Report (Oct 19 2009, 30 kb)
pdf icon Mid-Semester Paper (Oct 20 2009, 1053 kb)

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Contact Information

Project Team

Project Advisor and Client

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Created: Sep 21 2009
Content updated: Nov 21 2009

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