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Biomedical Engineering
Design Projects

Cryogenic Tissue Pulverizer

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Project Overview

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Design a device to complete manual tissue preparation process for biochemical analysis. The device should freeze the tissue with liquid nitrogen and grind it to a powder.

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Project Status

In our third and final semester on this project, we finalized our prototype. One team built a timing circuit for the solenoid valve while the other team designed the grinding chamber, cooling chamber and pulverizing head. The UW-Machine Shop machined our parts from AutoCAD drawings. We have mounted the grinding and cooling chamber, assembled the electronics and connected all pneumatic parts. Initial testing of all components with mouse liver, liquid nitrogen, and the dry-ice/ ethanol bath occurred in our client’s lab.

Our project earned both Honorable Mention and a K-12 Outreach Award at Engineering EXPO, April 10 - 12, 2003. Final presentations occurred May 2, 2003 in the atrium of the Engineering Centers Building.

Previous website - Fall 2002, 2nd semester of project
Initial website - Spring 2002, 1st semester of project

Progress Report Archive.

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Project Timeline

Week Reporting Period Beginning Activities
1 January 24 Client contacted, reformation and organization of group
2 January 31 Divided tasks, patent proposal, prototype work
3 February 7 Patent, EXPO proposal, prototype working, chamber design
4 February 14 Patent Meeting, chamber design, circuit timer
5 February 21 Drawing for head and chamber, circuit timer
6 February 28 Presentation, drawings for chamber, circuit building
7 March 7 Midsemsester presentation given, design notebooks turned In
8 March 14 Timing circuit, machining parts
9 March 21 Spring break, machining parts
10 March 28 Circuit completed, machining completed, mounting work, EXPO preparation, insulation work
11 April 4 Completion of prototype, initial testing with cashews, EXPO preparation
12 April 11 Engineering EXPO
13 April 18 Planning testing
14 April 25 Testing, preparing poster and final paper
15 May 2 Final presentations

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Presentations and Reports

pdf icon Product Design Specification (Version 6) (May 6 2003, 10 kb)
dwg icon AutoCAD of grinding chamber (May 6 2003, 52 kb)
dwg icon AutoCAD of grinding chamber rim (May 6 2003, 59 kb)
dwg icon AutoCAD of insulating chamber (May 6 2003, 76 kb)
sch icon PSpice of timing circuit (May 6 2003, 4 kb)
ppt icon Midsemester Presentation (May 6 2003, 2461 kb)
mpeg icon Video clip of timing circuit LED (May 6 2003, 352 kb)
mpeg icon Video clip of pneumatic components (May 6 2003, 352 kb)
mpeg icon Video clip of prototype grinding tissue (May 6 2003, 818 kb)
jpg icon Team picture with poster (May 6 2003, 127 kb)
jpg icon Final Poster (May 6 2003, 296 kb)
pdf icon Product Design Specification (Version 7) (May 6 2003, 10 kb)
pdf icon Final Design Paper (May 7 2003, 2160 kb)

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Contact Information

Project Team

Project Advisor and Client

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Owner: Willis Tompkins, Ph.D.
Author: Carla Maas
Created: Feb 14 2003
Content updated: May 7 2003

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