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Biomedical Engineering Design Projects

Feedback Stimulation to Stop Seizure Activity

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Project Overview

In order to abort epileptic seizures, or prevent their occurrence, electric shocks must be administered to the neurons where the seizure is originating. An algorithm, capable of measuring an electroencephalogram from slices of rat hippocampus, predict or detect a seizure, and send an electric stimulus to the neurons, is needed. The generation of the electric stimulus has to be effected in response to clear changes in the EEG that may preclude the occurrence of a seizure. The algorithm needs to check its own performance by operating in a feedback loop. Steve, Shikha, Ibrahim, and KatySteve, Shikha, Ibrahim, and Katy

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Project Status

Designing prediction algorithms in LabView. Determining best DAQ for stimulation.

Progress Report Archive.

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Project Timeline

Week Reporting Period Beginning Activities
1 January 20 Formed team
2 January 27 First client meeting
3 February 3 Investigated diffrent methods of data analysis, including pCLAMP, C++, MATLAB and LabView
4 February 10 Determined appropriate DAQ, wrote initial LabView applicaion
5 February 17 Tested input to DAQ on Rat Hippocampus Brain Slices
6 February 24 Worked on midsemester report
7 March 3 Program suructure laid out and work divided among team members
8 March 10 Sping Break
9 March 17 Worked on sectioning, prediction and detection sections of program
10 March 24 Worked on data acquisition and detection
11 March 31 Completed detection and prediction algorithm
12 April 7 Met with client to discuss project progress, researched analog output from DAQ
13 April 14 Got a faster DAQ and tested analog output
14 April 21 Completed sitmulation and feedback loop, worked on Final Report
15 April 28 Completed Final Report, Made poster, Presented

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Presentations and Reports

ppt icon Feedback Stimulation to Stop Seizure Activity (Feb 24 2006, 3221 kb)
pdf icon Midsemester Report (Mar 3 2006, 446 kb)
pdf icon User's Manual (Apr 28 2006, 337 kb)
pdf icon Final Report (Apr 28 2006, 1312 kb)
pdf icon PDS (Apr 28 2006, 24 kb)
jpg icon Final Presentation Poster (May 6 2006, 6594 kb)

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Contact Information

Project Team

Project Advisor and Client

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Owner: Willis Tompkins, Ph.D.
Author: Katy Reed
Webmaster: Andrew L. Wentland
Created: Jan 28 2006
Content updated: May 6 2006

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